HRCI & HRB announce successfully funded projects under Joint Funding Scheme

Picture by Shane O'Neill, SON Photographic

We’re delighted that the projects successfully funded in the latest round of the HRCI-HRB Joint Funding Scheme have been announced.  The successful projects will positively impact the lives of people with a wide range of health challenges such as cerebral palsy, cystinosis, arthritis, brain tumours, epilepsy and other health and social care issues including family carers.  The very nature of the scheme means that patients and families are at the heart of all the funded projects.

15 projects have been funded in this round of the scheme, to the tune of €3 million between the HRB and the participating HRCI members.  A total of 151 awards have been made since the inception of the scheme with a total investment of €25 million.

Congratulations to our member charities who were successful in their applications for funding.

Our colleagues in the Health Research Board have today launched a press release celebrating the launch of the Scheme HRB press release JFS HRB-HRCI-2022

Below is a list of all funded projects in this round of the Scheme:

Evaluation of a novel drug combination treatment for nephropathic cystinosis in a new cystinotic rat model.     

Co-funding charity: Cystinosis Ireland

Host institution: University of Auckland

Lead applicant: Dr Jennifer Hollywood

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Investigating the potential of CTNS-mRNA loaded nanoparticles as a new therapeutic strategy for nephropathic cystinosis.

Co-funding charity: Cystinosis Ireland

Host institution: University Hospitals Leuven and KU Leuven

Lead applicant: Prof Elena Levtchenko

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Counting the cost: The contribution of older carers in Ireland and impact of caring on mental health and wellbeing of carers

Co-funding charity: Family Carers Ireland

Host institution: Trinity College Dublin

Lead applicant: Dr Christine McGarrigle

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Participation in physical activity: what really matters to adolescents with physical disability?

Co-funding charity: Central Remedial Clinic

Host institution: RCSI University of Medicine and Health Sciences

Lead applicant: Dr Ailish Malone

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An investigation into the prevalence and experience of psychopathology and mental disorders among children and adolescents with cerebral palsy

Co-funding charity: Central Remedial Clinic

Host institution: RCSI University of Medicine and Health Sciences

Lead applicant: Dr Jennifer Ryan

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Sustaining activity with arthritis (SAWA) following an Arthritis Ireland Be active with arthritis (BAWA) exercise programme

Co-funding charity: Arthritis Ireland

Host institution: RCSI University of Medicine and Health Sciences

Lead applicant: Prof Suzanne McDonough

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Retinal Dystrophy in Ciliopathies (RDCilia): modelling patient mutations to decipher disease mechanisms, interpret Variants of Uncertain Significance, and uncover therapeutics

Co-funding charity: Fighting Blindness

Host institution: University College Dublin

Lead applicant: Dr Oliver Blacque

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Surgery, radiotherapy, chemotherapy, but now what? Exploring the rehabilitation needs of people with brain tumours in Ireland

Co-funding charity: Breakthrough Cancer Research

Host institution: RCSI University of Medicine and Health Sciences

Lead applicant: Dr Kathleen Bennett

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Pathways to Improving Transition to Adult Services & Enhancing Self-Management in Adolescents with Cystic Fibrosis: A New Era of Treatments

Co-funding charity: Cystic Fibrosis Ireland

Host institution: NUI Galway

Lead applicant: Dr Caroline Heary

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Ex vivo autologous stem cell gene therapy for Multiple Sulfatase Deficiency

Co-funding charity: MSD Action Foundation

Host institution: Childrens Hospital of Philadelphia

Lead applicant: Dr Rebecca Ahrens-Nicklas

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Advanced, automated compound screening for the identification of therapeutic agents in Multiple Sulfatase Deficiency.

Co-funding charity: MSD Action Foundation

Host institution: Fraunhofer ITMP

Lead applicant: Dr Lars Schlowata

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Combining HDAC6 inhibitors with KRAS inhibitors for the treatment of Non-Small Cell Lung Cancer (NSCLC)

Co-funding charity: Irish Cancer Society

Host institution: University of Limerick

Lead applicant: Dr Caitriona Dowling

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Patient-led development of a “Patient Reported Outcomes” instrument to improve health-related quality of life in patients with Glomerular Disease – PRO-GD

Co-funding charity: Irish Kidney Association

Host institution: University College Cork

Lead applicant: Dr Michelle O’Shaughnessy

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Long non-coding RNAs: regulators of epileptogenesis and potential targets for therapy

Co-funding charity: Epilepsy Ireland

Host institution: University College Dublin

Lead applicant: Dr Gary Brennan

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Predicting and monitoring outcomes in Autoimmune Encephalitis (POTA)

Co-funding charity: Epilepsy Ireland

Host institution: RCSI University of Medicine and Health Sciences

Lead applicant: Prof Norman Delanty

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