Past Rounds
A total of 151 awards have been made since the inception of the scheme with a total investment of €25 million.
While no differentiation is made between charities or disease areas, the scheme has been particularly beneficial for rare diseases where research being undertaken internationally may be limited.
Round 11 Joint Funding Scheme 2022
| Charity | Title | Principle Investigator | Research Institution |
|---|---|---|---|
| Cystinosis Ireland | Evaluation of a novel drug combination treatment for nephropathic cystinosis in a new cystinotic rat model. | Dr Jennifer Hollywood | University of Auckland |
| Family Carers Ireland | Counting the cost: The contribution of older carers in Ireland and impact of caring on mental health and wellbeing of carers | Dr Christine McGarrigle | TCD |
| Central Remedial Clinic | Participation in physical activity: what really matters to adolescents with physical disability? | Dr Ailish Malone | RCSI |
| Central Remedial Clinic | An investigation into the prevalence and experience of psychopathology and mental disorders among children and adolescents with cerebral palsy | Dr Jennifer Ryan | RCSI |
| Arthritis Ireland | Sustaining activity with arthritis (SAWA) following an Arthritis Ireland Be active with arthritis (BAWA) exercise programme | Prof Suzanne McDonough | RCSI |
| Cystinosis Ireland | Investigating the potential of CTNS-mRNA loaded nanoparticles as a new therapeutic strategy for nephropathic cystinosis. | Prof Elena Levtchenko | University Hospitals Leuven and KU Leuven |
| Fighting Blindness | Retinal Dystrophy in Ciliopathies (RDCilia): modelling patient mutations to decipher disease mechanisms, interpret Variants of Uncertain Significance, and uncover therapeutics. | Dr Oliver Blacque | UCD |
| Breakthrough Cancer Research | Surgery, radiotherapy, chemotherapy, but now what? Exploring the rehabilitation needs of people with brain tumours in Ireland | Dr Kathleen Bennett | RCSI |
| Cystic Fibrosis Ireland | Pathways to Improving Transition to Adult Services & Enhancing Self-Management in Adolescents with Cystic Fibrosis: A New Era of Treatments | Dr Caroline Heary | NUIG |
| MSD Action Foundation | Ex vivo autologous stem cell gene therapy for Multiple Sulfatase Deficiency | Dr Rebecca Ahrens-Nicklas | Childrens Hospital of Philadelphia |
| MSD Action Foundation | Advanced, automated compound screening for the identification of therapeutic agents in Multiple Sulfatase Deficiency. | Dr Lars Schlotawa | Fraunhofer ITMP |
| Irish Cancer Society | Combining HDAC6 inhibitors with KRAS inhibitors for the treatment of Non-Small Cell Lung Cancer (NSCLC) | Dr Caitriona Dowling | UL |
| Irish Kidney Association | Patient-led development of a “Patient Reported Outcomes” instrument to improve health-related quality of life in patients with Glomerular Disease – PRO-GD | Dr Michelle O'Shaughnessy | University of Galway |
| Epilepsy Ireland | Long non-coding RNAs: regulators of epileptogenesis and potential targets for therapy | Dr Gary Brennan | UCD |
| Epilepsy Ireland | Predicting and monitoring outcomes in Autoimmune Encephalitis (POTA) | Prof Norman Delanty | RCSI |
| DEBRA Ireland | A pain and wound management approach for RDEB patients via a functionalized collagen-based hydrogel dressing with controlled release of painkillers | Prof Wenxin Wang | UCD |
| Conor Foley Neuroblastoma Cancer Research Foundation | Development of mRNA Vaccines for Children with High-Risk Neuroblastoma | Dr Olga Piskareva | RCSI |
| Breakthrough Cancer Research | Developing an innovative patient-centred xenograft model of multiple myeloma and its use in testing novel antagonists of JAM-A signalling | Dr Ann Hopkins | RCSI |
| Cystic Fibrosis Ireland | Cystic Fibrosis Liver Disease (CFLD); predicting and prescribing in the era of CFTR modulators | Dr Emer Fitzpatrick | UCD |
Round 10 Joint Funding Scheme 2020
| Charity | Title | Principal Investigator | Research Institution |
|---|---|---|---|
| Cystic Fibrosis Ireland | Exploring diet quality in Cystic Fibrosis - enablers and barriers to eating a healthy diet in CF. | Dr Audrey Tierney | University of Limerick |
| Breakthrough Cancer Research | Utilising proteomics-derived data in establishing predictive biomarker signatures to assist therapeutic decision-making in Multiple Myeloma | Professor Peter O’Gorman | University College Dublin |
| CARD | To identify the underlying mechanisms involved in driving the distinct pathogenesis observed in PsA and RA, and to define how these impacts on therapeutic response | Professor Ursula Fearon | Trinity College Dublin |
| Breakthrough Cancer Research | Getting a Handle on Non-Canonical Polycomb Repressor Complex 1 (nc-PRC1) Dysfunction in Oncogenesis. | Professor Maureen J. O’Sullivan | Trinity College Dublin |
| The Alzheimer Society of Ireland | Including best practices and the voices of experience in developing post-diagnostic dementia support guidelines for people with an intellectual disability. | Prof Mary McCarron | Trinity College Dublin |
| Irish Thoracic Society | Correcting Pulmonary Immunity through manipulation of CFTR | Professor Joe Keane | Trinity College Dublin |
| Breakthrough Cancer Research | An investigation of the utility of exhaled breath condensate to detect sub-clonal mutations in early stage lung adenocarcinoma | Professor Bryan Hennessy | Royal College of Surgeons in Ireland |
| Irish Nephrology Society | Improving the diagnostic rate and prognostic value of genomic testing in polycystic kidney disease | Prof. Gianpiero Cavalleri | Royal College of Surgeons in Ireland |
| Fighting Blindness | High-throughput sequencing of inherited and multifactorial macula disease associated genes and risk factors allows identification of genetic interactions and Modifiers | Prof Frans Cremers | Radboud University |
| Multiple Sulfatase Deficiency Action Foundation | Development of pharmacological chaperones stabilizing FGE for therapeutic intervention in Multiple Sulfatase Deficiency | Prof. Thomas Dierks | Bielefeld University |
Round 9 Joint Funding Scheme 2018
| Charity | Title | Principle Investigator | Research Institution | Amount |
|---|---|---|---|---|
| Diabetes Ireland | Towards novel anti-infective with enhanced wound-healing for diabetic foot infections : Co2 releasing star shaped micro biocidal polymers | Dr Deirdre Fitzgerald-Hughes | Royal College of surgeons in Ireland | €207,33 |
| Research Motor Neuron | Novel Neurophysical Biomarkers of Heterogeneous Network Degeneration in Motor Neuron Disease for Quantifying the Progression and Outcome in Clinical Trials | Dr Bahman Nasseroleslami | Trinity College Dublin | €341,62 |
| Research Motor Neuron | Incorporation of sensor technology to provide clinical meaningfulness for existing standardised measurement scales in Amyotrophic Lateral Sclerosis | Dr Deirdre Murray | Trinity College Dublin | €213,89 |
| AlphaOne | The role of sialylated-alpha-1 antitrypsin in resolution of acute and chronic inflammation | Dr Emer Reeves | Royal College of Surgeons in Ireland | €319,32 |
| Epilepsy Ireland | The microbiome as an environmental trigger for autoimmune epilepsy (MICA) | Professor Gianpiero Cavalleri | Royal College of Surgeons in Ireland | €171,35 |
| Fighting Blindness | Elucidation of the role of SARM1 in retinal homeostasis and oxidative stress induced retinal degeneration | Dr Sarah Doyle | Trinity College Dublin | €341,78 |
| Irish Thoracic Society | Evaluating a novel macrolide based early intervention in the clinical management of chronic | Professor Fergal O’Gara | University College Cork | €115,00 |
| Irish Cancer Society | Preoperative Exercise to Improve Fitness in Patients Undergoing Complex Surgery for Cancer of the Lung or Oesophagus | Professor Juliette Hussey | Trinity College Dublin | €326,75 |
| MSD Action Foundation | Compound library screening in a zebrafish model of MSD to identify novel therapeutic compounds | Professor David Rubinsztein | University of Cambridge | €105,71 |
| MSD Action Foundation | Autophagy induction as a novel therapeutic strategy for MSD | Professor Andrea Ballabio | Fondazione Telethon | €98,90 |
| Breakthrough Cancer Research | Evaluation of the role of MxA and ISGylation in chemosensitivity in oesophageal cancer | Professor Sharon McKenna | University College Cork | €155,71 |
| Breakthrough Cancer Research | Gold-drug: Targeting a novel dual inhibitor drug with gold nanoparticles for improving radiation response in oesophageal cancer | Professor Jacintha O’Sullivan | Trinity College Dublin | €331,86 |
| Breakthrough Cancer Research | Combining Electrochemotherapy with a Toll Like receptor agonist for the treatment of lung cancer | Dr Patrick Forde | University College Cork | €158,29 |
Round 8 Joint Funding Scheme 2016
| Charity | Principle Investigator | Title |
|---|---|---|
| Diabetes Ireland Research Alliance | Prof Timothy O’Brien | Identifying the Aetiology of Diabetic Progenitor Cell Dysfunction in Osteoporosis |
| Irish Cancer Society, Alzheimer Society of Ireland, Diabetes Ireland & The Irish Heart Foundation | Prof David Hevey | Peer-to-peer motivational interview intervention for smoking, alcohol and physical activity among at-risk adolescents in low SES communities: A Feasibility trial |
| Cystinosis Ireland | Dr Minnie Sarwal | Targeting Autophagy in Nephropathic Cystinosis |
| Cystinosis Ireland | Prof Elena Levtchenko | Unravelling the mechanisms of Azoospermia and potential future treatments in male Cystinosis patients |
| Epilepsy Ireland | Prof David Henshall | MicroRNAs in the mechanism of ketogenic diet therapies and as biomarkers in paediatric Epilepsy |
| Irish Nephrology Society | Prof Mark Little | AVERT: Autoimmunity Relapse Prediction Using Multiple Parallel Data Sources |
| Fighting Blindness | Prof James Loughman | Pioneering Advances for Control of Myopia in Children- The Shield Initiative |
| Fighting Blindness | Prof Jane Farrar | Application of Next Generation Sequencing for the Genetic Characterisation of Irish Retinal Degeneration Patients |
| Arthritis Ireland | Prof Anthony Gerry Wilson | An Investigation of the mechanisms linking C5orf30 with tissue damage in Rheumatoid Arthritis |
| Arthritis Ireland | Prof Ursula Fearon | Resolution of inflammation by metabolic reprogramming in the inflamed joint |
| The Irish Thoracic Society | Prof Joseph Keane | Towards host-directed therapies to overcome immune impairment in cigarette smokers during mycobacterial infection |
| Muscular Dystrophy Ireland | Professor Kay Ohlendieck | Comparative mass spectrometric profiling of the dystrophin complexome in normal versus pathological muscles with differing degrees of fibre degeneration |
| Muscular Dystrophy Ireland | Dr Melissa Bowerman | Role of TWEAK/Fn14 pathway in mediating muscle pathology in SMA |
| St Patricks Mental Health Hospital | Prof Declan McLoughlin | Ketamine for Relapse Prevention in Recurrent Depressive Disorder: a randomised, controlled pilot trial (The KINDRED Trial) |
| Breakthrough Cancer Research | Dr Mark Tangney | Bacteria in Human Tumours |
Round 7 Joint Funding Scheme 2014
| Charity | Research Institution | Principal Investigator | Title |
|---|---|---|---|
| Alpha One | RCSI | Dr Emer P. Reeves | Altered lipid raft cholesterol content contributes to the dysregulated activity of neutrophils in alpha-1 antitrypsin deficiency |
| Alpha One | RCSI | Professor Noel McElvaney | Alpha-1 antitrypsin deficiency: Which is important phenotype, level, activity or all three? |
| Fighting Blindness | University College Dublin | Dr Breandan Kennedy | Identification of drugs that can safely and effectively maintain visual function in models of inherited retinal degeneration |
| Fighting Blindness | Queen’s University Belfast | Dr Giuliana Silvestri | Inherited Retinal Degenerations: All Ireland Retinal Degenerations Partnership (AIRDP) |
| Royal Victoria Eye and Ear | Royal College of Surgeons in Ireland | Professor Conor Murphy | Restoring immune balance in patients with patients with primary Sjogrens Syndrome (pSS) by modulating microRNA expression |
| Irish Thoracic Society | University College Cork | Professor Fergal O’Gara | Investigate the impact of bile aspiration on chronic respiratory infection – Bile Paradigm |
| Cystinosis Ireland | The University of Auckland | Professor Alan J. Davidson | Modelling cystinosis with human stem cells and the therapeutic potential of aspartate |
| Cystinosis Ireland | University of Florida | Professor Anuj Chauhan | Drug Eluting Contact Lenses for Cystinosis Therapy |
Round 6 Joint Funding Scheme 2013
| Charity | Principal Investigator | Project Title |
|---|---|---|
| Alpha One Foundation | Dr Emer P. Reeves | Post-translational modifications modify the anti-inflammatory |
| effect of alpha-1 antitrypsin | ||
| Children’s Fund for Health Ltd | Dr Sally Ann Lynch | Identification of the genetic causes of developmental delay with mitochondrial dysfunction in the Irish Traveller population |
| Epilepsy Ireland | Dr Naomi Elliott | The collaborative development of an evidence-based educational resource for self-disclosure strategies for people with epilepsy. (How-To-Tell) |
| Fighting Blindness | Prof. Jane Farrar | Genetic characterisation of a cohort of Irish retinal degeneration patients |
| Friends of the Rotunda | Professor Fergal Malone | The HANDLE Study: HEMODYNAMIC Assessment in pregnancy and neonatal Echocardiography assessment. A study identifying Abnormal Hemodynamic Profiles in Pregnancy as a Predictor of Adverse Obstetric Outcome and Characterisation of Neonatal Myocardial Performance in Infants. |
| Irish Cancer Society | Professor Pamela Gallagher | Self-Management for Head and Neck Cancer Survivors: Living Well With and Beyond HNC |
| Irish Thoracic Society | Prof Noel Gerard McElvaney | Ignoring the Nonsense – Personalised Medicine for Genetic Lung Disorders |
| Irish Thoracic Society | Dr Barry Plant | Clinical implications and utility of an endotoxin-tolerant state in cystic fibrosis |
Round 5 Joint Funding Scheme 2012
| Charity | Principal Investigator | Project Title | Research Institution |
|---|---|---|---|
| Alpha One Foundation | Dr Emer Reeves | Regulation of neutrophil membrane receptor profile and signalling by serum alpha-1 antitrypsin. | RCSI |
| Children’s Fund for Health | Prof. Eileen Treacy | Galactosaemia, a modifiable multi-system glycosylation disorder? | Children’s University Hospital Temple Street |
| Irish Cancer Society | B. Therese Kinsella | Thromboxane (TX)A2 -mediated PRK1 signalling in Prostate Cancer: | University College Dublin |
| Fighting Blindness | Prof Jane Farrar | Exploration of AAV-delivered gene therapies for LHON | TCD |
| Brainwave | Professor Agnes Higgins | An evaluation of the role of the Epilepsy Specilist Nurse and the impact on patient quality of life | RCSI |
| Brainwave | Dr Veronica Lambert | Demystify the veil of secrecy: a mixed method inquiry of parent-child dialogue about epilepsy and its associated stigma | Dublin City University |
| Research Foundation Royal Victoria Eye and Ear Hospital | Dr Caroline Jefferies | Profilling Toll-loke receptor responses in patients with primary Sjogren’s syndrome | RCSI |
| The Alzheimer Society of Ireland | Brian Lawlor | Cognitive function, caregiver stress an cortisol: Mechanisms and implications for prvention of adverse health consequences in spouse | Trinity College Dublin |
| National Chilldren’s Research Centre/Children’s Medical and Research Foundation | Dr Sean Ennis | The characterization of recessive mutations in homozygous haplotypes implicated in Autism Sepctrum Disorders | National Chrildren’s Research Centre, Crumlin Hospital |
| Bee For Battens , The Saoirse Foundation | Dr Jonathan Cooper | Glial dysfunctino in muktiple forms of NCL: new directions for therapy | Institute of Psychiatry, Kings College London |
| Bee For Battens , The Saoirse Foundation | Steven J Gray | Global Gene Transfer for the treatment of Batten Disease | The University of North Carolina at Chapel hill |
Round 4 Joint Funding Scheme 2011
| Charity | Principal Investigator | Host Institution | Project Title | Duration |
|---|---|---|---|---|
| Alpha One | Emer Reeves | RCSI | Control of lipid induced granule exocytosis in neutrophils: therapeutic potential of alpha-1 antitrypsin. | 3 Years |
| Alpha One | David Bergin | RCSI | The role of carbohydrate residues in Alpha-1 antitrypsin anti-protease and anti-inflammatory properties. | 3 Years |
| Brainwave | David C. Henshall | RCSI | Genome-wide DNA methylation analysis of hippocampus from patients with pharmacoresistant temporal lobe epilepsy. | 1 Year, 6 Months |
| Cystic Fibrosis Association of Ireland | Eileen Savage | UCC | National Prevalence of Depression and Anxiety in Patients with cystic fibrosis and Parents: Impact on Health and Quality of Life. | 3 Years |
| Cystic Fibrosis Association of Ireland | Marguerite Clyne | UCD | The role of mucus and mucins in mediating Pseudomonas aeruginosa colonization of the cystic fibrosis lung. | 3 Years |
| Diabetes Federation of Ireland | Ronan Conroy | RCSI | What factors influence self-care and Quality of Life in young Irish adults (aged 23-30) with Type 1 diabetes? | 1 Year |
| Fighting Blindness | Peter Humphries | TCD | Exploration of the candidacy of RPE65 in the etiology of adRP with choroidal involvement | 3 Years |
| Fighting Blindness | Jane Farrar | TCD | Stem cell therapies for the treatment of diverse retinal disorders. | 3 Years |
| Irish Cancer Society | Ciaran Morrison | NUIG | Centrosome amplification and radiosensitisation of prostate cancer cells. | 3 Years |
| Irish Cancer Society | Laura Barkley – Elliman | NUIG | Therapeutic microRNA control of Prostate Cancer growth. | 1 Year, 6 Months |
| Multiple Sclerosis Ireland | Una Fitzgerald | NUIG | Polymer-mediated delivery of endoplasmic reticulum stress altering siRNA to oligodendroyctes in a cerebellar rat brain slice model of de- and remyelination. | 3 Years |
| National Childrens Research Charity | Sally Ann Lynch | UCD | Indentifying recessive genes for primary ciliary dyskinesia, microepaly and dilated cardiomyopathy. | 2 years |
| National Childrens Research Charity | Sean Ennis | NCRC | Genomics of paediatric autism spectrum disorder | 3 Years |
Round 3 Joint Funding Scheme 2009
| Charity | Principal Investigator | Project Title | Duration |
|---|---|---|---|
| Alpha One | Prof Noel G McElvaney | Accelerated neurophil apoptosis is associated with alpha-1 antitrypsin deficiency | 3 Years |
| Alpha One | Dr Catherine Greene | Phosphatidylinositol 3-Kinasd (PI3K): a molecular target of ER stress induced by Z alpha -1 antitrypsin? | 3 Years |
| Association of Friends of St. Patricks Hospital | Prof Paul Fearon | Measuring quality of care in an Irish Mental Health Service Context | 3 Years |
| Brainwave: The Irish Epilepsy Association | Dr Evelyn T Burke | Heritability of cognitive endophenotypes in temporal lobe epilepsy: A neuropsychological investigation | 1 Year 6 months |
| Brainwave: The Irish Epilepsy Association | Dr Gianpiero Cavalleri | A pharmacogenomic study of chronic refractory epilepsy | 3 Years |
| Children’s Medical and Research Foundation | Dr Maureen J O’Sullivan | The role of Epigenetic Modification and miRNAs in the Development of Pediatric Gastrointestinal Stromal tumour (GIST) | 3 Years |
| Cystinosis Foundation Ireland | Dr Philip Newsholme | Molecular mechanisms of muscle myopathy and pancreatic beta cell dysfunction associated with Cystinosis: Determination of optimal approaches for cell protection | 3 Years |
| Duchenne Ireland | Dr Helge Amthor | Can exon skipping therapy restore the mitrochondiral metabolism in animal models for DMD | 1 Year |
| Duchenne Ireland | Prof Volker Straub | Identifying the biodistribution of antisense oligonucleotides in the mdx mouse by Magnetic Resonance Imaging | 2 Years |
| Irish Cancer Society | Dr Mark Lawler | Hypermethylation in prostate cancer: further evaluation of GSTP1, SFRP2 and IGFBP3 as prognostic biomarkers and unmasking of epigenetically controlled miRNAs | 3 Years |
| Irish Cancer Society | Dr Rosemary O’Connor | To determine how RACK1 regulations cell migration during tissue morpohgenesis and tumorigenesis using 3D culture model systems | 3 Years |
| Irish Cancer Society | Prof Afshin Samali | Uncoupling of death receptor-induced nuclear factor kappa B activation from apoptosis | 3 Years |
Round 2 Joint Funding Scheme 2007
| Charity | Principal Investigator | Project Title | Duration |
|---|---|---|---|
| Alpha One | Prof N.G.McElvaney | Anti-inflammatory effect of Alpha 1-antitrypsin on the phagocytic neutrophil | 3 Years |
| Irish Heart Foundation | Prof J Feely | Choice of antihypertensive agent in newly diagnosed patients and in those patients not responding to therapy | 2 Years |
| Irish Heart Foundation | Dr B Hynes | Cardiac Angiogenesis: “Cell Based Bypass” of chronic vascular occlusions | 2 Years |
| Cystic Fibrosis | Dr C Gallagher | Gender Differences in Muscle Dysfunction and Electrical Muscle Stimulation in Cystic Fibrosis | 3 Years |
| Cystinosis | Dr Patrick Harrison | Development of an in vitro gene repair kit: towards a cure for cystinosis | 3 Years |
| Cystinosis | Dr Minnie Sarwal | Investigation of a Mechanism That Can Prevent Renal Injury in the Patients with Nephropathic Cystinosis. | 3 Years |
| DEBRA | Dr Jane Farrar | Evaluation of RNAi-based therapeutic approaches for dominant dystrophic Epidermolysis Bullosa | 3 Years |
| Diabetes Federation of Ireland | Sean Dinneen | The Galway Diabetic Foot Study: Epidemiology, Cost, Feasibility, and Implications for Clinical Practice and Policy | 3 Years |
| Fighting Blindness | Jane Farrar | Exploration of stem cell-based therapies for retinal degenerations | 3 Years |
| Irish Cancer Society | Tom Cotter | Redox regulation of apoptosis modulating survival pathways in re-current tumours | 3 Years |
| Irish Cancer Society | Shaun McCann | Infusion of mesenchymal stem cells in patients with steroid resistant acute grade II to IV GvHD: a prospective double-blind randomized study | 3 Years |
Round 1 Joint Funding Scheme
| Charity | Principal Investigator | Project Title | Duration |
|---|---|---|---|
| Research Institute for a Tobacco Free Society | Professor Luke Clancy | ‘The effect of the Irish workplace smoking ban on birth weight and gestational age at birth’. | 1 Year |
| Research Institute for a Tobacco Free Society | Dr. Patrick Goodman | ‘A study of environmental tobacco smoke exposure within unexempted premises – nursing homes as defined in the Public Health Acts 2002 and 2004’. | 2 Years |
| Mater Foundation | Professor P. Ronan O’ Connell | ‘Investigation of fibroblast gene expression profiles associated with the development of fibrostenosing phenotype in Crohns disease’. | 3 Years |
| Mater Foundation | Dr. Maria Byrne | The effect of Insulin therapy on beta cell survival in patients with Maturity onset diabetes of the young (MODY) 3′ | 3 Years |
| Alpha One Foundation | Thomas P. Carrol | ‘Elucidation of unfolded protein response pathways activated in lung and liver disease associated with XZ alpha-1 antitrypsin deficiency’. | 3 years |
| Alpha One Foundation | Catherine M. Greene | ‘Identification and characterisation of novel proinflammatory proteases that exacerbate lung disease associated with Z Alpha -1 antitrypsin deficiency’. | 3 Years |
| Muscular Dystrophy Ireland | Professor Kay Ohlendieck | ‘Identification of novel biomakers in dystrophic heart and muscle fibres using comparative proteconomics’ | 3 Years |
| Muscular Dystrophy Ireland | Joe Mooney | ‘Safety testing of an antisense oligonucleotide for exon 51 skipping in the treatment of Duchenne muscular dystrophy’. | 1 Year |
| Fighting Blindness | Mr. Stephen Beatty | ‘Spatial profile of macular pigment in relation to risk for age-related macular degeneration’. | 3 Years |
| Fighting Blindness | Brendan N. Kennedy | ‘Directing retinal stem cells to become functionally integrated coen photoreceptors in host retinas’. | 3 Years |
| Fighting Blindness | Marius Ader | ‘The development of cell based therapies for the treatment of photoreceptor degeneration in mouse models of retinitis pigmentosa’. | 3 Years |
| Fighting Blindness | Peter Humphries | ‘On the molecular pathology of retinal degradation caused by mutations within the IMPDH1 gene’. | 3 Years |
| Diabetes Federation of Ireland | Dr. Donal O’ Shea | ‘Adipocyte size and type 2 diabetes in obesity – a study of patients undergoing bariatric surgery’. | 3 Years |
| The Cystic Fibrosis Association of Ireland | Edward F. McKone | ‘Genetic modifiers of the cystic fibrosis phenotype’. | 3 Years |
| DEBRA Ireland | Professor Abhay Pandit | ‘A biodegradable nanoshell for targeted gene delivery of type VII collagen’. | 3 Years |
| Irish Cancer Society | Dermot Kelleher | ‘Tribbles homolog 3 a novel regulator of carcinogen signalling in oesophageal cells’. | 3 Years |
| Irish Cancer Society | Professor Mark Lawlor | ‘Identifying and evaluating novel methylation biomakers in prostate cancer’. | 3 Years |
| Irish Cancer Society | Sharon McKenna | Influence of Bcr-Abl on ER initiated apoptosis, and novel targeting strategies for Bcr-Abl expressing leukemias’. | 3 Years |
| Irish Cancer Society | Professor Gerald C. O’ Sullivan | Immune reactivity to foregut cancers- investigation into mechanism of oral tolerance’. | 3 Years |
| Irish Cancer Society | Dr. Wiliam Watson | ‘Proteonomic analsyis of urine from prostate cancer patients – translating the proteonome to clinical biomarkers’. | 3 Years |
| Irish Cancer Society | John Reynolds | ‘Identification and validation of early predcitive serums markers of response to neoadjuvent radiochemotherapy in rectal and oesophageal cancer’. | 3 Years |
| Irish Cancer Society | Verna Amberger – Murphy | ‘Investigation in signalling pathways in high grade glioma in order to predict responsiveness to tyrosine kinase inhibitors’. | 3 Years |
| Irish Cancer Society | Margaret McGee | ‘Small molecule cycophilin A inhibitors as novel anticancer therapeutics’. | 3 Years |
| Irish Cancer Society | Professor Stephen Eustace | ‘A targeted contrast agent for multiple myeloma’ | 3 Years |
| Irish Heart Foundation | Dr. R Watson | ‘Analysis of neutrophil migratory potential as a predictive marker of human cardiac transplant rejection’. | 3 Years |
| Irish Heart Foundation | Thomas Barron | ‘Long term adherence to cardiovascular therapy in Irish populations’. | 2 Years |
| Irish Heart Foundation | Dr. Emma Stokes | ‘FAME – a randomized controlled trial of family mediated exercise intervention following a stroke’. | 3 Years |
| Irish Heart Foundation | Dr. James O’ Donnell | ‘Development of the endogenous thrombin potential assay as a novel approach to characterising global coagulation status in patients with arterial thrombosis’. | 2 Years |
| The Childrens Medical and Research Foundation | Professor JM Redmond | ‘Omega 3 fatty acid and glutamine pretreatment’. | 2 Years |
| The Childrens Medical and Research Foundation | Dr. Niamh O’ Sullivan | ‘Rapid early detection and molecular profiling of Pseudomonas aeruginosa isolates in Paediatric Cystic Fibrosis Patients | 3 Years |
| Meningitis Research Foundation | Dr. Ed Lavelle | ‘The identification of novel immunomodulatory factors from Neisseria memingitidis subgroup B’. | 3 Years |
| Asthma Society of Ireland | John L. Faul | ‘The role of natural T cells in human asthma’. | 3 Years |
| Cystinosis Foundation of Ireland | Dr. Donal Cairns | ‘Design, formulation and biological evaluation of novel prodrugs for the treatment of Cystinosis’. | 2 Years |
