Past Rounds
A total of 165 awards have been made since the inception of the scheme with a total investment of over €28 million.
While no differentiation is made between charities or disease areas, the scheme has been particularly beneficial for rare diseases where research being undertaken internationally may be limited.
Round 12 Joint Funding Scheme 2024
| Charity | Title | Principle Investigator | Research Institution |
|---|---|---|---|
| Multiple Sulfatase Deficiency Action Foundation | Optimising Therapeutic Agents to Treat Multiple Sulfatase Deficiency by Combining DNA Encoded Chemical Libraries and Fragments | Dr. Matthais Baud | University of Southampton |
| Irish Cancer Society | Glycosylation related changes in Multiple Myeloma and T cell Immunity (GlycoiMMuniTy) | Michael O'Dwyer | University of Galway |
| Fighting Blindness | Exploring Innate Immune Pathways in Photoreceptors in Retinal Degenerative Disease | Dr. Sarah Doyle | TCD |
| Breakthrough Cancer Research | Development of a Personalised Near Patient (PNP) Allogeneic NK-Cell Immunotherapy (PNP-NKimunnoT) for Platinum Resistant High-Grade Serous Ovarian Cancer | Dr Sharon O'Toole | TCD |
| Cystinosis Ireland | Sustained delivery of cysteamine prodrugs from nanobarrier contact lenses | Professor Anuj Chauhan | Colorado School of Mines |
| Irish Thoracic Society | Reducing SSc-ILD Progression - Targeting the effects of the pulmonary microenvironment | Bettina C Schock | QUB |
| Breakthrough Cancer Research | Hepato-ProMet: Proteomic assay of metabolic progression from steatosis to hepatobiliary cancer development | David J. Hughes | UCD |
| Breakthrough Cancer Research | ARMOR: tAilored peRsonalised Medicine fOr gastric canceR | Prof Jacintha O'Sullivan | TCD |
| The Alzheimer Society of Ireland | INNEACH: Intergenerational Programmes to enhance social connectivity for people living with dementia | Catherine Houghton | University of Galway |
| Cystinosis Ireland | Evaluate the protective effect of Astaxanthin for the treatment for nephropathic cystinosis in a cystinotic rat model | Minnie Sarwal | UCSF |
| The Rotunda Foundation | Restful Nights Happy Days: Promoting Healthy Sleep and Wellbeing Practices Among New Parents in Ireland | Anna Donnla O'Hagan | DCU |
| Fighting Blindness | Exploration of gene agnostic therapeutic approaches for ocular disorders modulating mitochondrial dysfunction | Prof G Jane Farrar | TCD |
Round 11 Joint Funding Scheme 2022
| Charity | Title | Principle Investigator | Research Institution |
|---|---|---|---|
| Cystinosis Ireland | Evaluation of a novel drug combination treatment for nephropathic cystinosis in a new cystinotic rat model. | Dr Jennifer Hollywood | University of Auckland |
| Family Carers Ireland | Counting the cost: The contribution of older carers in Ireland and impact of caring on mental health and wellbeing of carers | Dr Christine McGarrigle | TCD |
| Central Remedial Clinic | Participation in physical activity: what really matters to adolescents with physical disability? | Dr Ailish Malone | RCSI |
| Central Remedial Clinic | An investigation into the prevalence and experience of psychopathology and mental disorders among children and adolescents with cerebral palsy | Dr Jennifer Ryan | RCSI |
| Arthritis Ireland | Sustaining activity with arthritis (SAWA) following an Arthritis Ireland Be active with arthritis (BAWA) exercise programme | Prof Suzanne McDonough | RCSI |
| Cystinosis Ireland | Investigating the potential of CTNS-mRNA loaded nanoparticles as a new therapeutic strategy for nephropathic cystinosis. | Prof Elena Levtchenko | University Hospitals Leuven and KU Leuven |
| Fighting Blindness | Retinal Dystrophy in Ciliopathies (RDCilia): modelling patient mutations to decipher disease mechanisms, interpret Variants of Uncertain Significance, and uncover therapeutics. | Dr Oliver Blacque | UCD |
| Breakthrough Cancer Research | Surgery, radiotherapy, chemotherapy, but now what? Exploring the rehabilitation needs of people with brain tumours in Ireland | Dr Kathleen Bennett | RCSI |
| Cystic Fibrosis Ireland | Pathways to Improving Transition to Adult Services & Enhancing Self-Management in Adolescents with Cystic Fibrosis: A New Era of Treatments | Dr Caroline Heary | NUIG |
| MSD Action Foundation | Ex vivo autologous stem cell gene therapy for Multiple Sulfatase Deficiency | Dr Rebecca Ahrens-Nicklas | Childrens Hospital of Philadelphia |
| MSD Action Foundation | Advanced, automated compound screening for the identification of therapeutic agents in Multiple Sulfatase Deficiency. | Dr Lars Schlotawa | Fraunhofer ITMP |
| Irish Cancer Society | Combining HDAC6 inhibitors with KRAS inhibitors for the treatment of Non-Small Cell Lung Cancer (NSCLC) | Dr Caitriona Dowling | UL |
| Irish Kidney Association | Patient-led development of a “Patient Reported Outcomes” instrument to improve health-related quality of life in patients with Glomerular Disease – PRO-GD | Dr Michelle O'Shaughnessy | University of Galway |
| Epilepsy Ireland | Long non-coding RNAs: regulators of epileptogenesis and potential targets for therapy | Dr Gary Brennan | UCD |
| Epilepsy Ireland | Predicting and monitoring outcomes in Autoimmune Encephalitis (POTA) | Prof Norman Delanty | RCSI |
| DEBRA Ireland | A pain and wound management approach for RDEB patients via a functionalized collagen-based hydrogel dressing with controlled release of painkillers | Prof Wenxin Wang | UCD |
| Conor Foley Neuroblastoma Cancer Research Foundation | Development of mRNA Vaccines for Children with High-Risk Neuroblastoma | Dr Olga Piskareva | RCSI |
| Breakthrough Cancer Research | Developing an innovative patient-centred xenograft model of multiple myeloma and its use in testing novel antagonists of JAM-A signalling | Dr Ann Hopkins | RCSI |
| Cystic Fibrosis Ireland | Cystic Fibrosis Liver Disease (CFLD); predicting and prescribing in the era of CFTR modulators | Dr Emer Fitzpatrick | UCD |
Round 10 Joint Funding Scheme 2020
| Charity | Title | Principal Investigator | Research Institution |
|---|---|---|---|
| Cystic Fibrosis Ireland | Exploring diet quality in Cystic Fibrosis - enablers and barriers to eating a healthy diet in CF. | Dr Audrey Tierney | University of Limerick |
| Breakthrough Cancer Research | Utilising proteomics-derived data in establishing predictive biomarker signatures to assist therapeutic decision-making in Multiple Myeloma | Professor Peter O’Gorman | University College Dublin |
| CARD | To identify the underlying mechanisms involved in driving the distinct pathogenesis observed in PsA and RA, and to define how these impacts on therapeutic response | Professor Ursula Fearon | Trinity College Dublin |
| Breakthrough Cancer Research | Getting a Handle on Non-Canonical Polycomb Repressor Complex 1 (nc-PRC1) Dysfunction in Oncogenesis. | Professor Maureen J. O’Sullivan | Trinity College Dublin |
| The Alzheimer Society of Ireland | Including best practices and the voices of experience in developing post-diagnostic dementia support guidelines for people with an intellectual disability. | Prof Mary McCarron | Trinity College Dublin |
| Irish Thoracic Society | Correcting Pulmonary Immunity through manipulation of CFTR | Professor Joe Keane | Trinity College Dublin |
| Breakthrough Cancer Research | An investigation of the utility of exhaled breath condensate to detect sub-clonal mutations in early stage lung adenocarcinoma | Professor Bryan Hennessy | Royal College of Surgeons in Ireland |
| Irish Nephrology Society | Improving the diagnostic rate and prognostic value of genomic testing in polycystic kidney disease | Prof. Gianpiero Cavalleri | Royal College of Surgeons in Ireland |
| Fighting Blindness | High-throughput sequencing of inherited and multifactorial macula disease associated genes and risk factors allows identification of genetic interactions and Modifiers | Prof Frans Cremers | Radboud University |
| Multiple Sulfatase Deficiency Action Foundation | Development of pharmacological chaperones stabilizing FGE for therapeutic intervention in Multiple Sulfatase Deficiency | Prof. Thomas Dierks | Bielefeld University |
Round 9 Joint Funding Scheme 2018
| Charity | Title | Principle Investigator | Research Institution | Amount |
|---|---|---|---|---|
| Diabetes Ireland | Towards novel anti-infective with enhanced wound-healing for diabetic foot infections : Co2 releasing star shaped micro biocidal polymers | Dr Deirdre Fitzgerald-Hughes | Royal College of surgeons in Ireland | €207,33 |
| Research Motor Neuron | Novel Neurophysical Biomarkers of Heterogeneous Network Degeneration in Motor Neuron Disease for Quantifying the Progression and Outcome in Clinical Trials | Dr Bahman Nasseroleslami | Trinity College Dublin | €341,62 |
| Research Motor Neuron | Incorporation of sensor technology to provide clinical meaningfulness for existing standardised measurement scales in Amyotrophic Lateral Sclerosis | Dr Deirdre Murray | Trinity College Dublin | €213,89 |
| AlphaOne | The role of sialylated-alpha-1 antitrypsin in resolution of acute and chronic inflammation | Dr Emer Reeves | Royal College of Surgeons in Ireland | €319,32 |
| Epilepsy Ireland | The microbiome as an environmental trigger for autoimmune epilepsy (MICA) | Professor Gianpiero Cavalleri | Royal College of Surgeons in Ireland | €171,35 |
| Fighting Blindness | Elucidation of the role of SARM1 in retinal homeostasis and oxidative stress induced retinal degeneration | Dr Sarah Doyle | Trinity College Dublin | €341,78 |
| Irish Thoracic Society | Evaluating a novel macrolide based early intervention in the clinical management of chronic | Professor Fergal O’Gara | University College Cork | €115,00 |
| Irish Cancer Society | Preoperative Exercise to Improve Fitness in Patients Undergoing Complex Surgery for Cancer of the Lung or Oesophagus | Professor Juliette Hussey | Trinity College Dublin | €326,75 |
| MSD Action Foundation | Compound library screening in a zebrafish model of MSD to identify novel therapeutic compounds | Professor David Rubinsztein | University of Cambridge | €105,71 |
| MSD Action Foundation | Autophagy induction as a novel therapeutic strategy for MSD | Professor Andrea Ballabio | Fondazione Telethon | €98,90 |
| Breakthrough Cancer Research | Evaluation of the role of MxA and ISGylation in chemosensitivity in oesophageal cancer | Professor Sharon McKenna | University College Cork | €155,71 |
| Breakthrough Cancer Research | Gold-drug: Targeting a novel dual inhibitor drug with gold nanoparticles for improving radiation response in oesophageal cancer | Professor Jacintha O’Sullivan | Trinity College Dublin | €331,86 |
| Breakthrough Cancer Research | Combining Electrochemotherapy with a Toll Like receptor agonist for the treatment of lung cancer | Dr Patrick Forde | University College Cork | €158,29 |